Product Overview
HepG2 is a human cell line isolated from a hepatocellular carcinoma of 14 year old male donor. HepG2 cells are used in a wide range of studies, from the oncogenesis to the cytoxicity of substances on the liver
These cells can be used for (i) the study of carcinogenesis as a surrogate for liver toxicity, (ii) the analysis of signaling events, (iii) molecular biology and (iv) protein-based assays. These immortalized hepatic cell lines can be used in place of biopsies for research purposes.
These HepG2 cells are homogenous and grow robustly in cell culture. Vial contains approximately 500,000 cells. Shipped with dry ice.
Publications
Thrombospondin 2 is a Key Determinant of Fibrogenesis in Non-Alcoholic Fatty Liver Disease
Kimura, T et al. | Liver International 2024 FEB.
Department of Medicine, Shinshu University School of Medicine.
Department of Biological Sciences and Bioengineering, Indian Institute of Technology.
Comparison of Amine-Modified Polymeric Stationary Phases for Polar Metabolomic Analysis Based on Unified-Hydrophilic Interaction/Anion Exchange Liquid Chromatography/High-Resolution Mass Spectrometry (Unified-HILIC/AEX/HRMS)
Ikeda, K et al. | Mass Spectrometry 2024 JAN.
Department of Systems Life Sciences, Kyushu University.
Division of Metabolomics/Mass Spectrometry Center, Medical Research Center for High Depth Omics, Kyushu University.
Hydroxyapatite Nanocoating on Calcium Peroxide Microparticles for Sustained Oxygen Release
Tomioka, D et al. | Chemistry of Materials 2023
Division of Applied Chemistry, Graduate School of Engineering, Osaka University.
Advanced Photonics and Biosensing Open Innovation Laboratory, Osaka University.
Decellularized liver hydrogel enhances cell engraftment in orthotopic hepatocyte transplantation by promoting cell-cell interaction and angiogenesis.
Udagawa, D et al. | Research Square 2023 MAY.
Keio University.
Relationship between clock gene expression and CYP2C19 and CYP3A4 with benzodiazepines.
Tani, N et al. | Human & Experimental Toxicology 2023 APR.
Graduate School of Medicine. Osaka Metropolitan University.
Effect of methamphetamine on clock genes and drug-metabolizing enzyme expression.
Tani, N et al. | Human & Experimental Toxicology 2022 AUG.
Graduate School of Medicine. Osaka Metropolitan University.
A Novel Approach to Orthotopic Hepatocyte Transplantation Engineered With Liver Hydrogel for Fibrotic Livers, Enhancing Cell-Cell Interaction and Angiogenesis
Udagawa, D et al. | Cell Transplantation 2024 MAY
Department of Surgery, Keio University School of Medicine, Tokyo
Fundamental Innovative Oncology Core, National Cancer Center Research Institute, Tokyo.
Protocols & Documentation
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