Product Overview

Cystic fibrosis is caused by mutations in the gene encoding the cystic fibrosis transmembrane conductance regulator (CFTR) protein, which is involved in mucus production. This genetic disorder primarily affects the lungs, pancreas, liver, kidneys, and intestines.

Primary donor fibroblast cells were collected from a 19-year-old male of Caucasian descent. Cells were reprogrammed to a pluripotent state through our patented method using non-integrating episomal DNA with our proprietary mix of transcription factors and small molecule chemistry. This delivers the safest clinical starting point with the lowest chance of insertional mutagenesis while delivering consistency, reprogramming efficiency, and flexibility.

We reprogram starting cells without the transcription factors c-Myc and Lin28, which are linked to neoplastic formation. This effectively lowers the clinical risk profiles of downstream differentiated cells.

Vial contains approximately 500,000 cells. Shipped with dry ice.