Human Adipose-Derived Mesenchymal Stem Cells

SKU: CR1004-500 Category:

Human Adipose-Derived Mesenchymal Stem Cells

$725.00

Cryopreserved vial of human adipose-derived mesenchymal stem cells (~500,000 cells)

Quantity

Typically ships in:
1 - 2 business days

SKU: CR1004-500 Category:

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Product Overview

Cells derived from adult human lipoaspirate tissue collected during elective surgical liposuction procedures and then programmed using our patented virus-free method using episomal DNA and our proprietary mix of vectors, excluding Myc and Lin28 transcription factors. Adipose-derived mesenchymal cells (AdMSCs) are the most commonly used mesenchymal stem cells for clinical applications.

The cell line was validated for pluripotency based on colony morphology, alkaline phosphatase expression and expression of SSEA-4. Cells are free of Mycloplasma and exhibit classical morphology and growth characteristics. Vial contains approximately 500,000 cells. Shipped with dry ice.

AdMSCs have shown significant promise in treating autoimmune and neurodegenerative diseases, vascular and metabolic diseases, bone and cartilage regeneration and wound defects. These cells have been reported to differentiate into many different lineages including chondrogenic, osteogenic, adipogenic and neural cells.

Cell Characteristics

Coming Soon

Stability & Storage

Temperature 
 Storage Time
Human Adipose-Derived Mesenchymal Stem Cells
-80°C (preferably in the vapor phase of a liquid nitrogen storage unit)
12 months
Human Mesenchymal Stem Cell Expansion Media (not included)
4°C
3 months
Human Chondrogenic Differentiation Media (not included)
4°C
3 months
Complete Media (see Media Formulation Instructions)
2-8°C
Not applicable

Avoid repeated freeze-thaw cycles for cells. Avoid repeated exposure to room temperature and light for media.

Publications

Reversal of Pulmonary Fibrosis: Human Umbilical Mesenchymal Stem Cells from Wharton's Jelly versus Human-Adipose-Derived Mesenchymal Stem Cells.
Chu, KA et al. | International Journal of Molecular Sciences 2023 APR.
Department of Internalm Medicine, Kaohsiung Veterans General Hospital.
College of Medicine, National Sun Yat-sen University
Institute of Anatomy and Cell Biology, National Yang Ming Chiao Tung University

Exosomes derived from human adipose-derived stem cells alleviate hepatic ischemia-reperfusion (I/R) injury through the miR-183/ALOX5 axis.
Gong, Y et al. | FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology 2023 MAR.
Department of Hepatobiliary Surgery, Third Military Medical University (Army Medical University)

Exosomes Secreted by Wharton’s Jelly-Derived Mesenchymal Stem Cells Promote the Ability of Cell Proliferation and Migration for Keratinocyte
Yu, H et al. | International Journal of Molecular Sciences 2024 APR
Department of Pediatrics, Chang Gung University College of Medicine
Department of Medical Education and Research, Kaohsiung Veterans General Hospital
Department of Dental Technology, Shu-Zen Junior College of Medicine and Management

Fermented Garlic Extract Increases Oxygen Consumption and UCP-1 mRNA Expression in Human Adipose-Derived Stem Cells
Park, E et al. | Cell Journal 2019 OCT
Department of Bioengineering, Nagaoka University of Technology
Department of Biofood Science and Biotechnology, Chungbuk Provincial University.

Low power laser irradiation and human adipose-derived stem cell treatments promote bone regeneration in critical-sized calvarial defects in rats
Wang YH et al. | PLOS ONE 2018 APR
Department of Medical Research, College of Medicine, Kaohsiung Medical University.

Protocols & Documentation

Download: Product Information Sheet

Overview

Cells isolated from red marrow collected from a single adult human donor and then passaged three times to assure consistency. Vial contains approximately 500,000 cells. Shipped with dry ice.

Bone marrow-derived mesenchymal cells (BMSCs) contribute to the homeostasis of musculoskeletal tissue as well as support for the growth and differentiation of primitive hemopoietic cells.

BMSCs are extremely versatile and have been used in a host of tissue differentiation
applications including but not limited to adipogenic, chondrogenic, osteogenic and neural cell like conversions. These cells can be used for a range of tissue engineering and regenerative medicine applications.

cell type

Neural Cells, PSC-Derived, Pluripotent Stem Cells

Application

Cell Culture, Differentiation

Brand

STEMdiff

Area of Interest

Disease Modeling, Drug Discovery and Toxicity Testing, Neuroscience, Cell Therapy Development

Recommended products

Product Information

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Cells
Growth type
Derivation
Doner age
Doner ethnicity
Genes expressed
Karyotype
STR
Tumorigenic
Expression markers
Additional comments
Cell Media
None
Growth Factors
Activity (primary)
Specific activity
Molecular weight
Purity
Endotoxin concentration
Conjugate
Form
Formulation
GeneID
Accession number
Amino acid sequence
Species reactivity

Documentation

Product Sheet

Certificate of Analysis

Satety Data Sheet

Protocol

Data pending from client

Data pending from client

Data pending from client

Data pending from client

Data pending from client

Data pending from client

References

Rúben Luz, Rita Cordeiro, ..., Ralph Urbatzka
Marine Drugs | 2024 Sep 10

"Abstract: A ligand (HL) was synthesized from the pyridoxal hydrochloride (vitamin B6 form) and 1-(2-Aminoethyl)piperidine in one single step. The metal complexes [Zn(L)(Bpy)]NO 3 (1), [Cu(L)(Bpy)]NO 3 (2), and [Co(L)(Bpy)]NO 3 (3) were prepared by tethering HL and 2,2'-bipyridine. The synthesized HL and metal complexes 1-3 were thoroughly characterized using spectroscopic techniques such as 1 H NMR, 13 C NMR, FTIR, EI-MS, molar conductance, and magnetic moment, in addition to CHN elemental analysis" Read More

Hend A. Hekal, Maha M. Salem, Hayam A. Abd El Salam
BMC Chemistry | 2024 Sep 18

"Abstract: Mammary gland (MCF-7;# ATCC HTB-22 ), colorectal adenocarcinoma (Caco-2; # ATCC HTB-37 ), hepatocellular carcinoma (HepG-2; # ATCC HB-8065 ), and human lung fibroblast (WI-38; # ATCC CCL-75 ).. The ATCC cell line was obtained via the Holding Company for Biological Products and .."
Read More

Yong Zhang, Shaowei Han, ..., Junfei Jin
Animal Cells and Systems | 2024 Sep 17

"Abstract: A ligand (HL) was synthesized from the pyridoxal hydrochloride (vitamin B6 form) and 1-(2-Aminoethyl)piperidine in one single step. The metal complexes [Zn(L)(Bpy)]NO 3 (1), [Cu(L)(Bpy)]NO 3 (2), and [Co(L)(Bpy)]NO 3 (3) were prepared by tethering HL and 2,2'-bipyridine. The synthesized HL and metal complexes 1-3 were thoroughly characterized using spectroscopic techniques such as 1 H NMR, 13 C NMR, FTIR, EI-MS, molar conductance, and magnetic moment, in addition to CHN elemental analysis" Read More