Product Overview
Cells derived from adult human lipoaspirate tissue collected during elective surgical liposuction procedures and then programmed using our patented virus-free method using episomal DNA and our proprietary mix of vectors, excluding Myc and Lin28 transcription factors. Adipose-derived mesenchymal cells (AdMSCs) are the most commonly used mesenchymal stem cells for clinical applications.
The cell line was validated for pluripotency based on colony morphology, alkaline phosphatase expression and expression of SSEA-4. Cells are free of Mycloplasma and exhibit classical morphology and growth characteristics. Vial contains approximately 500,000 cells. Shipped with dry ice.
AdMSCs have shown significant promise in treating autoimmune and neurodegenerative diseases, vascular and metabolic diseases, bone and cartilage regeneration and wound defects. These cells have been reported to differentiate into many different lineages including chondrogenic, osteogenic, adipogenic and neural cells.
Stability & Storage
| | |
Human Adipose-Derived Mesenchymal Stem Cells | -80°C
(preferably in the vapor phase of a liquid nitrogen storage unit) | |
Human Mesenchymal Stem Cell Expansion Media (not included) | | |
Human Chondrogenic Differentiation Media (not included) | | |
Complete Media (see Media Formulation Instructions) | | |
Avoid repeated freeze-thaw cycles for cells. Avoid repeated exposure to room temperature and light for media.
Publications
Reversal of Pulmonary Fibrosis: Human Umbilical Mesenchymal Stem Cells from Wharton's Jelly versus Human-Adipose-Derived Mesenchymal Stem Cells.
Chu, KA et al. | International Journal of Molecular Sciences 2023 APR.
Department of Internalm Medicine, Kaohsiung Veterans General Hospital.
College of Medicine, National Sun Yat-sen University
Institute of Anatomy and Cell Biology, National Yang Ming Chiao Tung University
Exosomes derived from human adipose-derived stem cells alleviate hepatic ischemia-reperfusion (I/R) injury through the miR-183/ALOX5 axis.
Gong, Y et al. | FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology 2023 MAR.
Department of Hepatobiliary Surgery, Third Military Medical University (Army Medical University)
Exosomes Secreted by Wharton’s Jelly-Derived Mesenchymal Stem Cells Promote the Ability of Cell Proliferation and Migration for Keratinocyte
Yu, H et al. | International Journal of Molecular Sciences 2024 APR
Department of Pediatrics, Chang Gung University College of Medicine
Department of Medical Education and Research, Kaohsiung Veterans General Hospital
Department of Dental Technology, Shu-Zen Junior College of Medicine and Management
Fermented Garlic Extract Increases Oxygen Consumption and UCP-1 mRNA Expression in Human Adipose-Derived Stem Cells
Park, E et al. | Cell Journal 2019 OCT
Department of Bioengineering, Nagaoka University of Technology
Department of Biofood Science and Biotechnology, Chungbuk Provincial University.
Low power laser irradiation and human adipose-derived stem cell treatments promote bone regeneration in critical-sized calvarial defects in rats
Wang YH et al. | PLOS ONE 2018 APR
Department of Medical Research, College of Medicine, Kaohsiung Medical University.
Protocols & Documentation
Download: Product Information Sheet